AZNAstraZeneca PLC American Depositary Shares

AstraZeneca PLC American Depositary Shares represent ownership in AstraZeneca PLC, a global biopharmaceutical company focused on the discovery, development, and commercialization of prescription medicines. AstraZeneca’s current business spans Oncology, Rare Diseases, and BioPharmaceuticals, including Cardiovascular, Renal & Metabolism, and Respiratory & Immunology. The company develops and markets treatments used across hospitals, clinics, and specialty care settings, serving patients and healthcare providers in major therapeutic areas with high unmet medical need. Its portfolio is built around branded medicines and regulated drug launches, with ongoing commercial activity across the United States, Europe, and other international markets. AstraZeneca PLC American Depositary Shares provide U.S. investors a way to hold an instrument linked to the company’s underlying shares while participating in the performance of one of the world’s largest research-driven drugmakers.